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Introduction About CRESTOR 10MG TABLET

CRESTOR 10MG TABLET is used in the management of high blood cholesterol levels. It is prescribed when diet and exercise does not result in adequate results. It contains a medicine called which is an anti-hyperlipidemic agent that works by blocking cholesterol production in the body. It also makes your body eliminate lipids particles from the blood.

By reducing blood cholesterol levels, this medicine is helpful is reducing cardiovascular risks and problems in blood circulation across the body. While taking CRESTOR 10MG TABLET, you must follow a cholesterol-lowering diet, lifestyle changes and regular physical activity as instructed by your doctor to achieve better results.

Before taking CRESTOR 10MG TABLET inform your doctor if you have any lung, liver, kidney or heart problems. You must also inform your doctor if you have diabetes, thyroid problems, or a family history of muscle disorders. Do not take CRESTOR 10MG TABLET if you are pregnant or breastfeeding without consulting your doctor.

CRESTOR 10MG TABLET may increase your blood sugar levels, especially in patients who are diabetic. It may also affect the way your liver works and so your doctor will closely monitor your blood sugar levels and liver functions while undergoing therapy with CRESTOR 10MG TABLET as a precaution.

The most common side effects of taking CRESTOR 10MG TABLET are muscle ache, constipation, stomach pain, dizziness, nausea and headache. Inform your doctor if you experience severe unexplained muscle pain, tenderness or weakness along with fever after taking CRESTOR 10MG TABLET.

How should I take CRESTOR 10MG TABLET? CRESTOR 10MG TABLET should be taken according to your doctor instructions. Always take it exactly as prescribed. The recommended dose of CRESTOR 10MG TABLET is 10mg taken with meals.

The most common side effects of taking CRESTOR 10MG TABLET are muscle pain, tenderness or weakness, back pain, headache, change in the amount of voice increased while taking CRESTOR 10MG TABLET, constipation, diarrhea, weight gain, fast heartbeat and abnormal vision, redness in the nose, ear or sinus, sore throat, cough, fever, chills, joint pain or pain, itching, rashes and vaginal discharge, nausea and stomach cramps and weakness.

How do I take CRESTOR 10MG TABLET? CRESTOR 10MG TABLET are usually taken orally with or without food. Swallow CRESTOR 10MG TABLET with a full glass of water. Do not crush or chew CRESTOR 10MG TABLET. Taking CRESTOR 10MG TABLET with food may reduce the absorption of cholesterol-lowering medication and increase the risk of stroke or heart attack. It may also affect the way liver works.

The amount of time CRESTOR 10MG TABLET takes to work with or after taking it depends on the drug and the dose. In case of the lower dose of CRESTOR 10MG TABLET, the risk of abnormal results is lower but the effect of the drug is typically long lasting. In case of the higher dose of CRESTOR 10MG TABLET, the risk is often higher but the effect is not as good. In such a situation, it is advised to take CRESTOR 10MG TABLET with a high fat meal (such as fat were you on high fat snacks)?

For patients who are diagnosed with high cholesterol levels and are prescribed cholesterol-lowering medication, the effectiveness of CRESTOR 10MG TABLET may be reduced by partial discontinuation of the drug. It may also also reduce the level of lipase in the body. This may allow the medication to work in the patient and not in the patient’s body, which may help to reduce the level of cholesterol in the patient.

In summary:

  • Take CRESTOR 10MG TABLET exactly as prescribed
  • Take CRESTOR 10MG TABLET with a low fat meal (such as fat were you on high fat snacks)?
  • In the case of increasing level of lipase, take CRESTOR 10MG TABLET with a high fat meal (such as fat were you on high fat snacks)?

In case of discontinuation of the medication, do not take it. Do not take it again after the full course of CRESTOR 10MG TABLET is completed.

How long does CRESTOR 10MG TABLET take to work? It usually starts working within a few days of taking it.

Crestor (Rosuvastatin) is a statin drug that lowers cholesterol levels and helps prevent cardiovascular events in patients with:

High-fat meals,oily stools, or stools, associated with cardiovascular events such as heart attack, heart failure, or stroke;

Diabetes, which lowers blood sugar levels;

Heart failure, which may cause arteries that constrict blood vessels;

Low-fat meals, which may help minimize the chances of side effects with foods that may restrict blood flow; and

Platelet-rich plasma, a type of genetic material that improves blood circulation to tissues.

Crestor is approved by the FDA to treat:

• cholesterol-related eye problems (such as retinitis pigmentosa), including macular degeneration and other vision-related disorders.

• stroke, heart, or blood vessel disease due to heart disease, including ischemic stroke, vascular occlusion, and deep vein thrombosis.

• uterine bleeding or abnormal bleeding after heavy or long-term use of certain medications, including blood thinners.

To avoid Crestor side effects, including serious stomach problems (such as nausea, stomach pain, or belching), weight loss, and changes in form, take it with food to minimize stomach upset.

It is important to follow the dosage instructions provided by your doctor and to take it with a full glass of water.

* Crestor is a generic medication containing rosuvastatin equivalent to rosuvastatin (Crestor) in the dose strength of 20 mg.

More information:

Rosuvastatin (Crestor) is used to lower levels of some lipid disorders (such as high-density lipoprotein cholesterol and low-density lipoprotein cholesterol) and to prevent cardiovascular events, including heart attack.

Rosuvastatin is available in tablet form and as a liquid suspension.

Rosuvastatin comes as an oral tablet or suspension, which is dissolved in a water-soluble form.

Rosuvastatin is available as a generic or a brand-name drug.

To learn more about Crestor, talk with your doctor, pharmacist, or health care provider.

, or stools associated with heart problems or hypertension;

• stroke, heart, or blood vessel disease due to heart disease, including ischemic stroke, vascular occlusion, and deep vein thrombosis;

• uterine bleeding or abnormal bleeding after heavy or long-term use of certain medications, including blood thinners;

• may choose to take Crestor with food as a supplement to minimize stomach upset;

• may choose to take Crestor with food as a supplement to minimize stomach upset; and

• may choose to take Crestor with food as a supplement to avoid Crestor side effects.

Crestor may be taken with or without food.

Crestor is a generic medication containing rosuvastatin equivalent to rosuvastatin (Crestor) in the dose strength of 20 mg.

Rosuvastatin (Crestor) is used to lower levels of some lipid disorders (such as high-density lipoprotein cholesterol and low-density lipoprotein cholesterol) and to prevent cardiovascular events, including heart attack, lung, or blood vessel disease.

Crestor Dosage Information

The Crestor Dosage Information (Table) for the treatment of Patients with Hyperlipidemia is as follows:

Crestor (Rosuvastatin) should be taken once daily at a dose of 10 mg.

The dose of Crestor should be adjusted according to the patient’s blood pressure and body weight. The treatment duration is 6-12 months.

The Crestor Dosage should not be changed without consulting your doctor.

Take Crestor regularly. The daily dosage of Crestor is 20-40 mg. This dosage is important to prevent the development of drug-induced hyperlipidemia. If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not take two doses at once.

You should not take more than one dose of Crestor at a time, and Crestor should be taken with food.

If you have any questions or concerns, you should consult your doctor.

If you are taking any other medication, ask your doctor or pharmacist for advice.

Do not stop taking this medication without consulting your doctor, even if you feel well. It may make the condition worse.

You should not take this medicine if you are allergic to Crestor, if you are using any other medications, or if you have an allergy to any of the other ingredients in the medicine. Ask your doctor or pharmacist for advice before you start taking this medication. If you are pregnant or breastfeeding, tell your doctor or pharmacist promptly.

Do not consume alcohol while you are taking this medication. Alcohol can increase the effect of this medication. If you are taking any other medications, including those that are not listed, discuss with your doctor or pharmacist.

If you have any questions, your doctor or pharmacist will probably give you a written prescription for this medication. Be sure to ask your doctor or pharmacist if you have any questions.

Inform your doctor if you have or have had any medical conditions. Your doctor will probably give you a different medicine with this medication.

If you experience any side effects from this medication, you should continue to take this medication as your doctor has told you. Common side effects include:

  • Headache
  • Nausea
  • Diarrhea
  • Fever
  • Vomiting
  • Bloating
  • Abdominal pain

Your doctor will probably start you on a low dose of this medication. Ingest the whole tablet, and take it at the same time every day.

Ask your pharmacist for a copy of the manufacturer’s information for the patient.

Take this medication by mouth as directed by your doctor, usually once daily.

If you are taking any other medications, your doctor may want to change the dose or monitor you carefully for side effects. Be sure to tell your doctor and pharmacist about all the medications you are taking, including prescription drugs, nonprescription drugs, and herbal products. If you have any questions, ask your doctor or pharmacist.

You should also inform your doctor if you have a history of allergies, or are pregnant, planning to become pregnant, or if you use alcohol or are breast-feeding.

Tell your doctor if you are using any of the following.

If you are using any of the other ingredients of this medication:

  • Corticosteroids: St. John’s wort.

AstraZeneca (AZ) today announced that it has signed a $3.9 million upfront and cash payment to Pfizer for a research and development agreement. This agreement, which was announced on November 26, will bring AZ's cholesterol and triglyceride business to the $2.5 billion market in 2021.

Pfizer had previously disclosed that its research program focused on the ability to prevent heart disease, and AZ's first-in-category cholesterol product, Crestor, is also a significant advancement in this area. AZ plans to pursue further studies on how Crestor improves cardiovascular outcomes.

AstraZeneca has been a leader in the cholesterol business since its founding in 1991. In 2001, AZ announced that its cholesterol business had a $2.9 billion market cap. The cholesterol business is driven by the growing prevalence of cardiovascular diseases and the need for new treatments for cardiovascular disease. The focus of AZ's research and development business is on developing new therapies that can improve cholesterol levels and potentially lower LDL cholesterol, the primary component of LDL (bad) cholesterol.

AZ has also been the leader in cardiovascular research and development, including the COX-2 (COX-2) inhibitor rosuvastatin, the first FDA-approved drug to treat high cholesterol, and the first FDA-approved drug to treat high triglycerides (fat) in adults and adolescents aged 18 years and older.

The AZ's research and development business is currently on a mission to advance new therapies to help people with cholesterol, heart disease, and stroke.

In a statement, AZ stated that it is in the process of setting up an "unfunded research-sponsored" company. The company is focused on developing a new therapy to lower LDL cholesterol, and will pursue additional studies to see if Crestor can be used safely to treat patients with coronary artery disease.

The $3.9 million upfront and cash payment will be made in cash. All payments are due on Nov. 31, 2021. The company's current and future activities will continue as normal.

For more information and to learn more about AZ's cholesterol and triglyceride business, please visit the AZ website at www. AZ.com. Additional information about its cholesterol and triglyceride business may be found at www.

View more at www. AZ.com/news/news-release.

SOURCE: AZ AstraZeneca

References

1. AstraZeneca's Crestor's Head-On Competition: New R& D Activities and Research, LLC, AstraZeneca, Inc. http://www.astrazeneca.com/crestor-news/2012/01/11/crestor-news-activity-research-crestor.html (accessed May 10, 2014). 2. AstraZeneca's Crestor: The Basics: R& D Activities and Research, LLC, AstraZeneca, Inc. 3. AZ's cholesterol and triglyceride business: The Basics: The Development of a New Drug to Lower LDL Cholesterol, a Comprehensive Review of the Current State of the Business of Rosuvastatin, by J. Lee, M. D. and M. S. (online) (accessed April 6, 2014). 4. AZ's cholesterol and triglyceride business: The Developing Therapies for Lipid Control, by J. 5. 6. AstraZeneca's Crestor: The Development of a New Drug to Lower LDL Cholesterol, a Comprehensive Review of the Current State of the Business of Rosuvastatin, by J. 7. AstraZeneca's Crestor: A Clinical Development and Research Study to Evaluate the Safety and Efficacy of Rosuvastatin, by A. J. Kesselheim, M. 8. AZ's cholesterol and triglyceride business: The Development of a New Drug to Lower LDL Cholesterol, by A. 9.